Potential of the Ethanolic Extract of Matoa Leaves (Pometia pinnata J.R. & G.Forst) against Staphylococcus aureus bacteria

  • Wahyu Margi Sidoretno Universitas Abdurrab
Keywords: Antibacterial activity, Pometia pinnata, Staphylococcus aureus

Abstract

Staphylococcus aureus is a bacterium that can cause several diseases in humans such as ulcers and wound infections. Matoa leaves contain phenolic and flavonoid compounds which are known to have antibacterial properties. The purpose of this study was to determine the antibacterial activity of the ethanolic extract of Pometia pinnata J.R. & G.Forst leaves against Staphylococcus aureus at concentrations of 10%, 20%, and 30%. This research was conducted by disc diffusion method on Mueller Hinton Agar (MHA) media. Antibacterial activity was measured by looking at the inhibition of the growth of S. aureus bacteria. Based on the results of the study, it was found that the ethanolic extract of matoa leaves was able to inhibit the growth of S. aureu bacteria with the average inhibition zones produced at concentrations of 10%, 20% and 30%, namely 11.06 mm, 15.07 mm, 16.07 mm and control ciprofloxacin positive was 28.10 mm. From the results above, it can be concluded that the ethanolic extract of matoa (Pometia pinnata) leaves has antibacterial activity against Staphylococcus aureus.

References

[1] Suharno, H.R Tanjung. Matoa, Yogyakarta, 2011
[2] Suedee, A, Phytocemichal Studies of Mimusopselengi and Pometia pinnata Leaf Extract with Anti HIV 1 Integrase Activity. Thesis. Songkla (TH): Prince of Songkla University, 2012
[3] Martiningsih, N. W., Widana, G. A. B., dan Kristiyanti, P. L. P, Skrining Fitokimia dan Uji Aktivitas Antioksidan Ekstrak Etanol Daun Matoa (Pometia pinnata) dengan Metode DPPH. Prosiding Seminar Nasional MIPA. Halaman 332 – 338, 2016
[4] Soedarto, Mikrobiologi Kedokteran. Jakarta: Sagung Seto, 2015
[5] Ngajow, M., Abidjulu, J., dan Kamu, V. S, Pengaruh Antibakteri Ekstrak Kulit Batang Matoa (Pometia pinnata) Terhadap Bakteri Staphylococcus aureus secara In vitro, Jurnal MIPA UNSRAT, Volume 2 (2): Halaman 128 – 132, 2013
[6] Zanuary, A.R., Efektivitas Daya Antibakteri Ekstrak Daun Matoa (Pometia Pinnata J. R. & G. Forst) Dalam Berbagai Konsentrasi Terhadap Pertumbuhan Streptococcus Mutans (secara invitro): Semarang, 2014
[7] Departemen Kesehatan Republik Indonesia, Suplemen 1 Farmakope Herbal Indonesia. Direktorat Jendral Pengawasan Obat dan Makanan, Jakarta, 2010
[8] Thermo Fisher Scientific, Dehydrated Culture Media, Mueller Hinton Agar, CM0337, OXOID, 2022
[9] Aryal, S. McFarland Standar-Principle, Preparation, Uses, Limitattions, Microbe Notes, 2021
[10] Torar, G.M.J., W.A. Lolo, dan G. Citraningtyas, Uji Aktivitas Antibakteri Ekstrak Etanol Biji Pepaya (Carica papaya L.) terhadap Bakteri Pseudomonas aeruginosa dan Staphylococcus aureus. Jurnal Ilmiah Farmasi, Vol. 6 No. 2, 2017
[11] Herawati, D. L.N, Sumarto, Cara Produksi Simplisia yang Baik, Bogor: Seafast Center, IPB, 2012
[12] Kuspradini, Harlinda., Pasedan, Whicliffe Fiernaleonardo Pasedan., &Wijaya, Irawan. Aktivitas Antioksidan dan Antibakteri Ekstrak Daun Pometia pinnata. Jurnal Jamu Indonesia. 1 (1) :26-34, 2016
[13] Lely, Nilda., Ayu, Anestia Meta & Adrimas. Efektifitas Fraksi Daun Matoa (Pometia pinnata J.R. Forst. & G. Forst.) Sebagai Antimikroba. Jurnal Ilmiah Bhakti Farmasi, 1 (1), 2016
[14] Ngajow, Mercy., Abidjulu, Jemmy & Vanda S. Kamu. Pengaruh Antibakteri Ekstrak Etanol Kulit Batang Matoa (Pometia pinnata) terhadap Staphylococcus aureus. Jurnal MIPA UNSRAT, Online 2 (2), 2013
[15] Tanaya, V., R. Retnowati dan Suratmo, Fraksi Semi Polar dari Daun Mangga Kasturi (Mangifera casturi Kosterm). Kimia Student Journal, Vol 1 No 1. Universitas Brawijaya, 2015
[16] Sutton, S, Measurement of Microbial Cells Bay Optial Density. Journal of Validation Technology. 17: 46-49, 2011
[17] Acumedia, Muller Hinton Agar, PI 7101. Rev 03, 2011
[18] Kee, J.L dan E. R. Hayes, Farmakologi Pendekatan Proses Keperawatan, Jakarta: Buku Kedokteran EGC, 1996
[19] Kaharap, A.D, Mambo C., dan Nangoy E, Uji Efek Antibakteri Ekstrak Batang Akar Kuning (Arcangelista lava Merr) terhadap Bakteri Staphylococcus aureus dan Escherichia coli. Jurnal e-Biomedik (eBm), Volume 4, Nomor 1. Universitas sam Ratulangi Manado, 2016
Published
2022-02-03
How to Cite
Sidoretno, W. (2022). Potential of the Ethanolic Extract of Matoa Leaves (Pometia pinnata J.R. & G.Forst) against Staphylococcus aureus bacteria. JPK : Jurnal Proteksi Kesehatan, 10(2), 107-112. https://doi.org/10.36929/jpk.v10i2.402