Formulation and Antioxidant Activity Testing of Carrot Seed Oil Microemulsion Spray

  • Nadya Putri Auliya Serawaidi Universitas Abdurrab, Pekanbaru, Indonesia
  • Yan Hendrika Universitas Abdurrab, Pekanbaru, Indonesia
  • Mahendra Mahendra Universitas Abdurrab, Pekanbaru, Indonesia
  • Evy Eryta Universitas Abdurrab, Pekanbaru, Indonesia
  • Atika Putri Universitas Abdurrab, Pekanbaru, Indonesia
Keywords: Carrot Seed Oil, Spray Formula, Antioxidant

Abstract

Carrot seed oil, rich in vitamin A, is known as an antioxidant, sun protectant, and anti-aging and skin rejuvenating agent. This research aims to evaluate the formulation and antioxidant potential of carrot seed oil spray. The research method consists of three stages: formulation, physical evaluation, and antioxidant activity test. The organoleptic test results showed color differences in the three formulas. All three formulas have a thick, oily consistency and the distinctive aroma of carrot seed oil. The average pH value of F1 is 7.4, F2 is 7.7, and F3 is 8.0. The viscosity value of F1 is 25.4 cP, F2 is 19.56 cP, and F3 is 31.66 cP. The antioxidant activity test shows that pure carrot seed oil has moderate antioxidant activity with an IC50 value of 240.9772 g/mL. The three carrot seed oil spray formulas showed weak antioxidant activity with IC50 values: F1 269.3943 g/mL, F2 316.1039 g/mL, and F3 442.6015 g/mL. Based on research, it can be concluded that pure carrot seed oil has moderate antioxidant activity, while the three carrot seed oil spray formulas have weak antioxidant activity.

References

[1] Amrun, H., M., Umiyah, U.,& U, E.UUji Aktivitas Antioksidan Ekstrak Air dan Ekstrak Metanol Beberapa Varian Buah Ketinu (Chrysophyllum cainito L.). JPK:Jurnal Proteksi Kesehatan, 2007, vol. 13, no. 1, pp. 45-50.
[2] Suiraoka, I. Penyakit Degeneratif. Yogyakarta: nuMed, 2012.
[3] Arianto, A., Bangun, H., Natasya, C., Yanti, D. W. I., & Siregar, P. Sunscreen Alami dan Anti Penuaan Kulit yang Efektif. JIF:Jurnal Internasional Farmasi, 2022, vol. 14, no. 1, pp.1–6.
[4] Fransisca, S. Leslie, W. dan Musnaini. Effectiveness Of Cream Formulation Of Carrot Seed Oil As Anti-Aging. Skripsi. SumateraUtara: Universitas Prima Indonesia, 2016.
[5] Mustarichie, R., Runadi, D. & Ramdhani, D. The antioxidant activity and phytochemical screening of ethanol extract, fractions of water, ethyl acetate, and n-hexane from mistletoe tea (Scurrula atropurpurea BL. dans). Asian Journal of Pharmaceutical and Clinical Research, 2017, vol. 10, no. 2, pp. 343–347.
[6] Shabrina, A., Pratiwi, A. R., & Muurukmihadi, M. Stabilitas Fisik dan Antioksidan Mikroemulsi Minyak Nilam Dengan Variasi Tween 80 dan PEG 400. Media Farmasi, 2020, vol.16, no. 2,185.
[7] Ashfia, F., Adriane, F., Sari, devi puspita, & Rusmini. Sediaan Footspray Anti Bau Kaki yang Ampas Kopi. JIF:Jurnal Internasional Farmasi, 2019, vol. 3, no. 1, pp. 28–33.
[8] Syaifuddin. Uji Aktivitas Antioksidan Bayam Merah (Alternanthera amoena voss.) Segar dan Rebus Dengan Metode DPPH (1,1 –diphenyl-2- picylhydrazyl). Skripsi, Semarang: Universitas Islam Negeri Walisongo, 2015.
[9] Arianto, A., Bangun, H., Natasya, C., Yanti, D. W. I., & Siregar. PSunscreen Alami dan Anti Penuaan Kulit yang Efektif. JIF:Jurnal Internasional Farmasi, 2022, vol. 14, no. 1, pp.1–6.
[10] Diharjo, S., Suyanti, S., & Sunarmani, S.Tingkat Kematangan Panen Buah Nenas Sampit untuk Konsumsi Segar dan Selai. JH:Jurnal Hortikultura, 2006, vol. 16, no. 3, pp. 80-704.
[11] Jufri, M dan Utami.Uji Stabilitas Sediaan Mikroemulsi Menggunakan Hidrolisat Pati sebagai Stabilizer. Pharmaceutical Sciences and Research, 2006, vol. 3, no. 1, pp. 8–21.
[12] Salwa, S., Abd Kadir, M. Bin, & Sulistyowati, Y. Formulasi dan Evaluasi Sediaan Spray Gel Tabir Surya Fraksi Etil Asetat Daun Cempedak (Artocarpus Integer (Thunb.) Merr.) dengan Kombinasi Basis Hpmc dan Karbopol 940. Jurnal Mahasiswa Kesehatan, 2020, vol. 2, no. 1, pp. 12-16.
[13] Hanani, E. Identifikasi Senyawa Antioksidan dalam Spons Callyspongia SP dari Kepulauan Seribu. Ejounal Ilmu Kefarmasian, 2017, no. 2.
[14] Sobari, E., & Fathurohman, F. Efektifitas Penyiangan Terhadap Hasil Tanaman Wortel (Daucus carota) Lokal Cipanas Bogor. Jurnal Biodjati, 2017, vol. 2, no. 1, https://doi.org/10.15575/biodjati.v2i1.1292
[15] Fariza, S. Isolasi dan Uji Aktivitas Antioksidan Senyawa Metabolit Sekunder Dari Ekstrak Metanol Kulit Batang Gerunggang (Cratoxylum arborencens (Vahl.) Blume). Skripsi, Riau: Sekolah Tinggi Ilmu Farmasi, 2018.
[16] Syaifuddin. ‘Uji Aktivitas Antioksidan Bayam Merah (Alternanthera amoena voss.) Segar dan Rebus Dengan Metode DPPH (1,1 –diphenyl-2- picylhydrazyl) Skripsi. Semarang: Universitas Islam Negeri Walisongo, 2015.
[17] Amrun, H., M., Umiyah, U.,& U, E.UUji Aktivitas Antioksidan Ekstrak Air dan Ekstrak Metanol Beberapa Varian Buah Ketinu (Chrysophyllum cainito L.). JPK: Jurnal Proteksi Kesehatan, 2007, vol. 13, no. 1, pp. 45-50.
[18] Korichi, R. & Tranchant, J. Decorative products. Handbook of Cosmetic Science and Technology, Third Edition. New York: Informa Healtcare, 2009.
[19] Molyneux, PThe Use of the Stable Free Radical Diphenylpicryl-hydrazyl (DPPH) for Estimating Antioxidant Activity. Songklanakarin Journal of Science and Technology, 2004, vol. 5, no.1, pp. 211–219.
[20] Sarker S.D., Latif Z., dan Gray A.I. Nat-ural products isolation. In: Sarker SD, Latif Z, & Gray AI, editors. Natural Products Isolation. 2nd ed. Totowa(New Jersey). Humana Press Inc, 2006.
Published
2024-08-18
How to Cite
SerawaidiN., HendrikaY., MahendraM., ErytaE., & PutriA. (2024). Formulation and Antioxidant Activity Testing of Carrot Seed Oil Microemulsion Spray. JPK : Jurnal Proteksi Kesehatan, 13(1), 92-97. https://doi.org/10.36929/jpk.v13i1.878