Lysis Test of Ascaris lumbricoides Eggs After Giving Ethanol Extract of Chinese Ketepeng Leaves (Cassia alata L.)
Abstract
soil or known as soil transmitted helminth (STH). Infection caused by these parasites can be eradicated by giving synthetic drugs and herbal medicines. One of the plants that can be used as herbal medicine is ketepeng cina (Cassia alata L.). chinese ketepeng leaves (Cassia alata L.) have one benefit, namely to treat intestinal worms. This study aims to determine the morphological changes of eggs Ascaris lumbricoides after the administration of ethanol extract of chinese ketepeng leaves (Cassia alata L.) with concentration 1%, 2%, 3%, 4%, 5%. The method used in this study is laboratory experiments. The results of this study indicate that the ethanol extract of chinese ketepeng leaves (Cassia alata L.) in concentrated 4% and 5% changes color in the eggs but there is no morphological change in eggs. From this study it can be concluded that the ethanol extract of chinese ketepeng leaves (Cassia alata L.) is not able to damage the morphologi of Ascaris lumbricoides worm eggs.
References
WHO. (2020). Soil-transmitted helminth infections, uploated 2 March 2020. (diakses 07 November 2020)
CDC. (2020). Paracites ascariasis (online) https://www.cdc.gov/parasites/ascariasis/index.html (diakses 07 November 2020)
Katzung, B. G. (1998). Farmakologi Dasar dan Klinik. Jakarta: EGC
Asmah. N, Halimatussakdiah dan Ulil Amna. (2020). Analisa Kandungan Senyawa Metabolit Sekunder Ekstrak Daun Ketepeng Cina (Cassiaalata L.)dari Bireum Bayeun, Aceh Timur Quimica: Jurnal Kimia Sains dan Terapan ISSN 2716-0963 Volume 2, Nomor 2 e-ISSN 2716-1218
Shargel L, and Yu ABC. (1988). Biofarmasetika dan Farmakokinetika Terapan. Edisi Kedua. Diterjemahkan oleh Fasich dan Siti Sjamsiah. Surabaya: Airlangga University Press
I.O. Ademola1 , and J.N. Eloff. (2011). Ovicidal and larvicidal activity of Cassia alata leaf acetone extract and fractions on Haemonchus contortus: In vitro studies, Pharmaceutical Biology, 2011; 49(5): 539–544 © 2011 Informa Healthcare USA, Inc. ISSN 1388-0209 print/ISSN 1744-5116 online DOI: 10.3109/13880209.2010.526948
Iman, F., Waluyo, J., dan Asyiah, I.N. (2015). Pengaruh Variasi Konsentrasi ekstrak Daun Ketepeng Cina (Cassia alata L.) Terhadap Mortalitas Cacing Ascaris suum Dewasa Secara In Vitro. repository.unej.ac.id.
Intannia, D., Amelia, R., dan Santoso, H. B. (2015). Pengaruh Pemberian Ekstrak Etanol dan Ekstrak n-Heksan Daun Ketepeng Cina (Cassia Alata. L) terhadap Waktu Kematian Cacing Pita Ayam (Raillietina Sp.) Secara In Vitro. Jurnal Pharmascience.
Kuntari, T. (2008). Daya Antihelmintik Air Rebusan Daun Ketepeng Cina (Cassia alata L.) Terhadap Cacing Tambang Anjing In Vitro. Jurnal Logika
Sherman IG, and Sherman VG. (1988). The Invertebrates Function and Form. New York; MacMillan Publishing Co. Inc
Harborne. (1987). Metode Fitokimia, Penuntun Cara Modern Menganalisis Tumbuhan. Terjemahan: K. Padmawinata, I. Sudiro. Bandung: Institut Teknologi Bandung
Molan, A. L., G. C. Waghorn, B. R. Min, and W. C. McNabb. (2000). The effect of condensed tanin from seven herbages on Trichostrongylus colubriformis larval migration in vitro. Folia Parasitol. 47:39–44.
Tiwow, D. 2013. Uji Efek Antihelmintik Ekstrak Etanol Biji Pinang (Areca catechu) Terhadap Cacing Ascaris lumbricoides dan Ascaridia galli Secara In Vitro. PHARMACON Jurnal Ilmiah Farmasi – UNSRAT Vol. 2 No. 02
Kalma. (2018). Studi kadar C-Reaktive Protein (CRP) Pada Penderita Diabetes Melitus Tipe 2. Jurnal Media Analis Kesehatan
Musa, F. F. (2014). Uji Efektifitas Antelmintik Ekstrak Etanol Daun Ketepeng Cina (Cassia alata L.) Terhadap Cacing Gelang Ascaris lumbricoides. Jurnal Pharmascience.
Bora, A. M., dan Samsuri. (2014). Vermisidal Dan Ovisidal Ekstrak Daun Pepaya Terhadap Cacing Ascaris suum Secara In Vitro. Jurnal Indonesia Medicus Veterinus.
Soedarto. (2016). Buku Ajar Parasitologi Kedokteran. Jakarta: Sagung Seto